This year, the scientific program is composed of 2 keynote lectures, 16 lectures and 2 short talks that are arranged in 4 sessions:
– CRISPRs for Attack and Defense
– Advances in Genome Editing
– CRISPRs as Discovery Tools
– Therapeutic Applications of Gene Editing

Finally, 2 panel discussions will allow speakers to discuss the scientific and therapeutic challenges of genome editing.

  • 1.45 – 2.00 pm Welcome & Opening remarks
  • 2.00 – 3.00 pm Opening Keynote Lecture
    Engineering smarter T cells, Carl H. JUNE
  • 3.30 – 5.00 pm Session I: CRISPRs for Attack and Defense
    Adaptation mechanisms in CRISPR-Cas immunity, Dipali SASHITAL
    Beyond CRISPR: anti-phage defense in the wild, Rotem SOREK
    Editing population genetics for vector control, Andrea CRISANTI
  • 9.30 am – 12.00 pm Session II: Advances in Genome Editing
    Base Editing: Genome Editing Without Double-Stranded DNA Cleavage, Nicole GAUDELLI
    Structures, mechanisms and engineering of CRISPR-Cas genome editors, Martin JINEK
    Genome Engineering Technologies for Programming and Recoding Organisms, Farren ISAACS
    RNA modulation by RNA-targeting Cas proteins, Gene YEO
  • 12.00 – 12.15 pm Short talk (selected from posters)
  • 1.30 – 3.30 pm Session III: CRISPRs as Discovery Tools
    CRISPR/Cas9 mediated genome editing in mice and its application for the study of reproduction, Mashito IKAWA
    New frontiers in functional genomics using high-throughput genome engineering, Neville SANJANA
    Lorenz MAYR
    CRISPR tools to study and fight pathogenic bacteria, David BIKARD
  • 4.00 – 5.00 pm Session IV: Panel discussion: Scientific Challenges for Genome Editing
  • 9.00 am – 12.00 pm Session V: Therapeutic Applications of Gene Editing
    Gene Editing for Primary Immunodeficiencies, Suk See DE RAVIN 
    Optimizing homology-directed repair of DNA breaks in hematopoietic stem cells, Paula CANNON
    CRISPR/Cas9 Gene Editing in Primary Human T Cells to Enhance the Efficacy of CAR T Cell Therapy, Crystal MACKALL
    Correction of Duchenne Muscular Dystrophy by Genome Editing, Eric OLSON
    Gene edited T cell therapies for leukaemia, Waseem QASIM
  • 12.00 – 12.15 pm Short talk (selected from posters)
  • 1.45 – 2.45 pm Session VI: Panel discussion: Therapeutic Challenges for Genome Editing
  • 2.45 – 3:45 pm Closing Keynote Lecture
    Functional Genomics to Study Cancer, David SABATINI
  • 3.45 – 4.00 pm Closing remarks